Research progress on pleiotropic neuroprotective drugs for traumatic brain injury

Traumatic brain injury (TBI) has become one of the most important causes death and disability worldwide. A series neuroinflammatory responses induced after TBI are key factors for persistent neuronal damage, but at same time, such inflammatory can also promote debris removal tissue repair TBI. The concept pleiotropic neuroprotection delves beyond single-target treatment approach, considering multifaceted impacts following This notion embarks deeper into research-oriented paradigm, focusing on multi-target interventions that inhibit post-TBI neuroinflammation with enhanced therapeutic efficacy. With an enriched comprehension TBI’s physiological mechanisms, this review dissects advancements in developing neuroprotective pharmaceuticals to mitigate aim is provide insights may contribute early clinical management condition.